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Strain Certification
A service of the UNC Mutant Mouse Regional Resource Center
Strain Name: B6.129P2-Kcnh5tm1Dgen/Mmnc
MMRRC ID #: 11629
Reference 1 (blue) : C57BL/6J
Reference 2 (red) : 129P2/OlaHsd
Gene location: Chr12 75,998,204 bp - 76,278,319 bp
Size of interval containing gene (includes ambiguous regions): 10.60 Mb ( 77.27 Mb - 87.86 Mb)

Notes for B6.129P2-Kcnh5tm1Dgen/Mmnc :

Genotyping for MMRRC#11629 was performed on ONE heterozygous male mouse that was one generation backcrossed onto C57BL/6J relative to the   original mice submitted to the MMRRC-UNC archive by the donating investigator.  When compared to C57BL/6J (Reference 1) and 129P2/OlaHsd (Reference 2) genotypes, MUGA genotyping indicated that the strain background was 99.6% C57BL/6J.  A single 10.6Mb interval heterozygous for 129P2/OlaHSD markers was identified on chromosome 12, adjacent to the Kcnh5 locus.  This region should span the location and the heterozygous mutation but because of the density of the array and the identity between the two references in this region,  the transition from C57BL/6J markers occurs after the Kcnh5 locus.  Genotyping for this sample is consistent with the information provided by the donating investigator on the strain detail sheet and confirms the inbred status of the strain.

  Ref 1 (blue) Ref 2 (red) Het Unknown (gray)
Genomic Size  2571.48 Mb   0.00 Mb   10.22 Mb   0.00 Mb
Genomic Fraction  99.60%   0.00%   0.40%   0.00% 
# markers 7810 0 36 0
informative markers  3116   0   12   
concordant calls  98.33%   0.00%   91.67%   
discordant calls  1.67%   0.00%   8.33%   

Strain Detail Sheet

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