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Strain Certification
A service of the UNC Mutant Mouse Regional Resource Center
Strain Name: B6;129-Egftm1Dle Tgfatm1Unc
MMRRC ID #: 11535
Date : July 21, 2011
Reference 1 (blue) : C57BL/6J
Reference 2 (red) : 129P2/OlaHsd
Gene location: Chr3 129,380,493 bp - 129,458,240 bp
Size of interval containing gene (includes ambiguous regions): 30.07 Mb (129.93 Mb - 160.00 Mb)
Gene location: Chr6 86,145,420 bp - 86,225,151 bp
Size of interval containing gene (includes ambiguous regions): 44.95 Mb ( 49.18 Mb - 94.14 Mb)

Notes for B6;129-Egftm1Dle Tgfatm1Unc:

Genotyping for MMRRC#11535 was performed on ONE homozygous male mouse that was 5 generations intercrossed within the strain relative to the original mice submitted to the MMRRC-UNC archive by the donating investigator.  When compared to C57BL/6J (Reference 1) and 129P2/E14 (Reference 2) genotypes, MUGA genotyping indicated that the strain background was very heterogeneous:  44.04% C57BL/6J, 23.16% 129P2/OlaHsd, and 30.43% heterozyous.  Two 129P2/OlaHsd  homozygous intervals were identified on Chromosome 3 (spanning the Egf locus) and on Chromosome 6 (spanning the Tgfa locus).   There is a small portion of the genome that is unknown (1.85%) that is likely due to prior breeding with HbEgf-/-mice. The strain background for this sample is consistent with the information provided by the donating investigator on the strain detail sheet.



  Ref 1 (blue) Ref 2 (red) Het Unknown (gray)
Genomic Size  1136.92 Mb  597.92 Mb  785.62 Mb   61.24 Mb
Genomic Fraction  44.04%   23.16%   30.43%   2.37% 
# markers 3453 1844 2357 192
informative markers  1325   735   1016   
concordant calls  91.09%   92.79%   88.58%   
discordant calls  8.91%   7.21%   11.42%   



Strain Detail Sheet

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